Figure 6.
Deconvolution of bulk transcriptomics by paired single-cell RNA-seq enables identification of cell-type-specific features
(A) Transcripts from bulk transcriptomics data analyzed as in Figure 2 were selected based upon increasing expression over time and consistent dynamics across all six donors in Experiment 1. Charts show normalized counts for hours since blood draw for the individual donors, indicated by color.
(B) Single-cell RNA-seq data (analyzed as in Figure 4) from all 10 donors in both experiments were queried for transcripts selected in (A) and plotted by cell type. Charts show the normalized and scaled RNA count (y axis) for hours since blood draw (x axis). Individual donors are indicated by color.