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Effects of Il6 absence on sex hormone levels: Circulating serum testosterone level (a); and testicular testosterone (b), DHT (c), and estradiol (d) concentration. Increased testosterone (p = 0.0381) and DHT (p = 0.0159) testicular levels in IL6KO mice. *p < 0.05, unpaired t-test or Mann–Whitney test. Values expressed as mean ± SEM. Results are representative of samples from 4 to 6 mice per group. DHT—dihydrotestosterone.
