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Global transcriptional patterns associated with androgen induced differentiation in HPr1-AR cells. (A) Volcano plots depicting expression changes at each time point (1 h, 24 h, 96 h) relative to untreated cells (n = 4 at each time point). (B) Venn diagram of DEGs identified at 24 and 96 h of DHT exposures. (C) Heatmap of top 100 luminal and basal differentiating genes as identified by Zhang et al.4. (D) Select enrichment plots from GSEA analysis comparing 96 h of DHT exposure to 0 h.
