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. 2021 Jun 1;11:11516. doi: 10.1038/s41598-021-91083-9

Table 2.

Diagnostic performance of the ECG criteria.

LVH criteria Reference: Echocardiogram Reference: Peguero-Lo Presti
Sensitivity (95% CI) Specificity (95% CI) PPV (%) NPV (%) F1 Score (%) McNemar test LVHa (comparing sensitivity) McNemar test no LVHb (comparing specificity)
Sokolow-Lyon voltage 28.2 (22.6–34.4) 92.6 (89.3–95.1) 72.3 65.3 40.6  < 0.0001  < 0.0001
Cornell voltage 35.3 (29.2–41.7) 89.7 (86.1–92.7) 70.2 66.9 47.0  < 0.0001  < 0.0001
Peguero-Lo Presti 51.9 (45.4–58.3) 82.1 (77.6–85.9) 66.5 71.3 58.3
Romhilt Estes 4 points 54.4 (47.8–60.8) 68.1 (62.9–72.9) 53.9 68.5 54.1 0.497  < 0.001
Romhilt Estes 5 points 44.4 (38.0–50.9) 79.2 (74.6–83.3) 59.4 67.5 50.8 0.042 0.275

Comparison of the performance of the ECG criteria aMcNemar test comparing other ECG criteria versus Peguero-Lo Presti in patient with LVH in echocardiogram; bMcNemar test comparing other ECG criteria versus Peguero-Lo Presti in patient without LVH in the echocardiogram; a and b = p < 0.05 indicates lack of agreement.

CI confidence interval; NPV negative predictive value; PPV positive predictive value.