Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 29;31(6):613–630. doi: 10.1038/s41422-020-00466-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — Oligopaint DNA FISH analysis of four representative loci before and after depletion of L1 RNA for 36 h in mESCs. a Scheme of relative chromosomal localizations and spatial distances of the four compartments labeled by Oligopaint DNA FISH probes. B1-rich domain: F. L1-rich domains: e, g, and q. b, c Representative images and quantification of the spatial distances between two labeled compartments are shown in b and c, respectively. Each dot in c represents a nucleus. In cells treated with L1 AMO, the median distance between the two B1 and L1 compartments e and F is significantly decreased compared to the control, while the median distance between the two L1 compartments g and q is significantly increased. Data are presented as means ± SD. n, number of nuclei analyzed. P values are calculated by the two-tailed Student’s t-test. Scale bars, 5 μm.