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. 2021 May 19;8:649748. doi: 10.3389/fmed.2021.649748

Table 4.

Moderator analysis for the effects of exercise on measurement outcomes.

Variables Muscle Strength Physical Performance Body Composition
Grip Strength Knee Extension Chair and Stand TUG Gait Speed ASM SMI Muscle Mass Lean Mass BODY FAT
SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI) SMD (95% CI)
Criteria
AWGS 0.23 (0.03–0.43) 0.32 (0.13–0.51) 0.55 (0.11–0.98) 0.69 (0.26–1.13) 0.55 (0.23–0.88) 0.25 (0.05–0.44) 0.18 (−0.13 to 0.49) 0.08 (−0.21 to 0.36) 0.53 (−0.25 to 1.31) 0.36 (−0.18 to 0.91)
EWGSOP 0.41 (0.15–0.67) 0.34 (−0.10 to 0.78) 0.54 (0.22–0.87) 0.79 (0.43–1.16) 0.64 (0.28–1.00) 0.47 (0.00–0.94) 0.49 (0.18–0.80) 0.19 (−0.20 to 0.57) 0.16 (−0.14 to 0.45) 0.16 (−0.22 to 0.54)
Sex
Female 0.39 (0.03–0.76) 0.39 (0.12–0.66) 0.91 (0.46–1.35) 0.95 (0.59–1.31) 0.25 (0.02–0.48) 0.27 (−0.07 to 0.62) 0.13 (−0.11 to 0.37 0.28 (−0.12 to 0.68) 0.55 (−0.26 to 1.37)
Male 0.97 (0.34–1.60) 1.08 (0.35–1.81) 0.39 (−0.22 to 0.99) 0.94(−0.59 to 2.48) 1.40 (0.73–2.06)*
Mixed 0.21 (0.03–0.39) 0.28 (0.05–0.51) 0.5 (0.30–0.81) 0.26 (0.26–0.86) 0.43 (0.15–0.70) 0.27 (0.03–0.50) 0.27 (0.02–0.52) 0.001 (−0.68 to 0.68) 0.13 (−0.25 to 0.52) 0.13 (−0.20 to 0.46)
Exercise type
RT 0.33 (0.14–0.51) 0.32 (0.09–0.54) 0.31 (0.02–0.61) 0.80 (0.37–1.23) 0.50 (0.19–0.81) 0.33 (0.13–0.52) 0.54 (0.15–0.74) 0.11 (−0.11 to 0.34) 0.16 (−0.14 to 0.45) 0.16 (−0.17 to 0.49)
RT+AE 0.24 (−0.02 to 0.50) 0.35 (0.01–0.68) 0.71 (0.33–1.08) 0.59 (0.23–0.96) 0.92 (0.35–1.50) 0.19 (−0.25 to 0.64) 0.18 (−0.20 to 0.55) 0.53 (−0.25 to 1.31) 0.50 (−0.42 to 1.42)
WBV 0.34 (−0.29 to 0.96) 0.88 (0.23–1.53) 0.90 (0.25–1.55) 0.61 (−0.02 to 1.25)
Exercise frequency
≥3 times/week 0.14 (−0.16 to 0.44) 0.46 (0.07–0.85) 0.72 (0.39–1.04) 0.79 (0.43–1.16) 0.85 (0.41–1.29) 0.68 (−0.18 to 1.55) 0.25 (−0.02 to 0.53) 0.24 (−0.18 to 0.65) 0.31 (−0.22 to 0.83)
<3 times/week 0.36 (0.16–0.55) 0.29 (0.10–0.48) 0.35 (0.06–0.64) 0.69 (0.26–1.13) 0.47 (0.19–0.85) 0.26 (0.08–0.43) 0.48 (0.06–0.90) 0.11 (−0.11 to 0.34) 0.18 (−0.19 to 0.55) 0.23 (−0.23 to 0.68)
Exercise duration
>12 weeks 0.39 (0.12–0.65) 0.33 (0.02–0.65) 0.77 (0.11–1.44) 0.38 (0.02–0.75) 0.25 (−0.04 to 0.54) 0.28 (−0.01 to 0.58) 0.19 (−0.20 to 0.57) 0.18 (−0.19 to 0.55) 0.18 (−0.27 to 0.62)
≤ 12 weeks 0.27 (0.06–0.47) 0.32 (0.11–0.53) 0.44 (0.19–0.68) 0.74 (0.48–1.00) 0.63 (0.35–0.92) 0.34 (0.11–0.57) 0.43(0.08–0.79) 0.08 (−0.21 to 0.36) 0.24 (−0.18 to 0.65) 0.34 (−0.17 to 0.86)
Session time
≤ 45min 0.14 (−0.09 to 0.37) 0.31 (−0.07 to 0.68) 0.44 (0.19–0.68) 0.66 (0.25–1.06) 0.55 (0.15–0.96) 0.35 (0.05–0.64) 0.29 (−0.01 to 0.59) 0.12 (−0.37 to 0.61) 0.07 (−0.31 to 0.46)
>45min 0.41 (0.19–0.65) 0.34 (0.12–0.56) 0.77 (0.11–1.44) 0.82 (0.44–1.19) 0.62 (0.33–0.92) 0.30 (0.07–0.53) 0.42 (0.04–0.79) 0.11 (−0.11 to 0.34) 0.24 (−0.09 to 0.58) 0.43 (−0.04 to 0.90)
Exercise intensity
Light 0.22 (−0.01 to 0.45 0.27 (−0.08 to 0.61) 0.58 (0.03–1.20) 0.24 (−0.11 to 0.59) 0.31 (0.02–0.60) 0.29 (−0.20 to 0.79) 0.06 (−0.59 to 0.71)
Moderate-vigorous 0.35 (0.09–0.61) 0.38 (0.13–0.62) 0.58 (0.26–0.90) 0.81 (0.57–1.05) 0.82 (0.48–1.16)* 0.32 (0.06–0.59) 0.30 (0.03–0.56)* 0.11 (−0.11 to 0.34) 0.18 (−0.189 to 0.552) 0.16 (−0.22 to 0.54)
Vigorous 0.50 (−0.37 to 1.37) 0.43 (−0.35 to 1.20) 0.33 (−0.16 to 0.82) 0.23 (−0.26 to 0.71) 0.44 (0.01 to 0.87) 0.28 (−0.21 to 0.77) 0.56 (−0.23 to 1.35) 0.24 (−0.18 to 0.65) 0.55 (−0.26 to 1.37)
Control group
Active 0.30 (0.08–0.53) 0.28 (0.01–0.54) 0.31 (0.001–0.61) 0.70 (0.41–1.00) 0.76 (0.38–1.15) 0.23 (0.04–0.41) 0.48 (0.13–0.83) 0.14 (−0.14 to 0.42) 0.22 (−0.09 to 0.53) 0.48 (−0.41 to 1.38)
Passive 0.30 (0.07–0.53) 0.38 (0.13–0.63) 0.74 (0.41–1.06) 0.85 (0.24–1.46) 0.34 (0.12–0.56) 0.61 (0.03–1.20) 0.21 (−0.10 to 0.52) 0.15 (−0.46 to 0.77) 0.17 (−0.20 to 0.55)
*

p < 0.05.

AE, aerobic exercise; ASM, appendicular skeletal muscle; AWGS, Asia Working Group for Sarcopenia; EWGSOP, European Working Group on Sarcopenia in Older People; RT, resistance training; TUG, timed up and go; WBV, whole-body vibration training.