Table 1.
Auxologic, biochemical and imaging findings in the twins.
| At presentation | Age 3 years | Normal values | ||||
|---|---|---|---|---|---|---|
| Twin 1 | Twin 2 | Twin 1 | Twin 2 | |||
| Auxology | Weight (kg) (SDS) | 1.98 (-2.53) | 1.6 (-3.5) | 14.35 | 16.6 | |
| Length (cm) (SDS) | ND | ND | 98.0 | 98.6 | ||
| Biochemical results | Insulin (µIU/mL) | <0.2 | <0.2 | ND | ND | 5-29.1 |
| C –peptide (ng/ml) | 0.1 | 0.1 | 0.31 | 0.32 | 0.9-7.1 | |
| Insulin Abs (%)* | Negative | Negative | <7.0 | |||
| GAD2 Abs (U/mL)* | Negative | 7.2 | <1.0 | |||
| IA2 Abs (U/mL)* | Negative | Negative | <0.75 | |||
| HbA1C (%) | 8.2 | 7.4 | 6.5 | 7.0 | <5.6 | |
| TSH (mIU/L) | >150 | >150 | 2.52 | 24.5 | 0.64-6.27 | |
| FT4 (pmol/L) | <1.3 | 1.84 | 19.3 | 17.6 | 11.4-20.9 | |
| FT3 (pmol/L) | 1.99 | 8.1 | 3.5-6.5 | |||
| Imaging | Abdominal US | ND | Normal | Normal | Normal | |
| Kidney US with a 4 mm cyst. | Echogenic kidneys with small cortical cysts | Echogenic kidneys with small cortical cysts | Echogenic left kidney with a 4 mm cyst. | Normal | ||
| Thyroid US | Normal size and location | Normal size and location | ||||
| Brain MRI | Normal | Normal | ||||
ND, not done, US, ultrasound.
*Pancreatic antibodies were collected at 23 days.