Table 1.
Relevant characteristics of the enrolled study participants (n=38) of the Interdisciplinary Group for Advanced Research on Birth Outcomes-DBT India Initiative (GARBH-Ini) Cohort, Haryana, India.
| Characteristics | Term(n=20) n (%) or Median (IQR) | Preterm(n=18) n (%) or Median (IQR) |
|---|---|---|
| Clinical and demographic | ||
| Maternal age (year) | 23 (21,26) | 22 (20,25) |
| Weight at enrollment (kg) | 46.1 (40.9,53.5) | 46.0 (41.5,50.2) |
| BMI at enrollment | 19.61 (18.52,22.49) | 19.10 (17.48,20.62) |
| BMI category | ||
| Underweight | 5 (25.00%) | 8 (44.44%) |
| Normal | 11 (55.00%) | 8 (44.44%) |
| Overweight | 2 (10.00%) | 0 (0.00%) |
| Obese | 2 (10.00%) | 2 (11.11%) |
| Gravidity | ||
| Primigravida | 6 (30.00%) | 7 (38.89%) |
| Multigravida | 14 (70.00%) | 11 (61.11%) |
| History of vaginal discharge | ||
| Present | 1 (5.00%) | 1 (5.56%) |
| Absent | 19 (95.00%) | 17 (94.44%) |
| History of bleeding per vagina | ||
| Present | 0 (0.00%) | 0 (0.00%) |
| Absent | 20 (100.00%) | 18 (100.00%) |
| History of diarrhea | ||
| Present | 0 (0.00%) | 1 (5.56%) |
| Absent | 20 (100.00%) | 17 (94.44%) |
| Socioeconomic status | ||
| Upper middle class | 2 (10.00%) | 3 (16.67%) |
| Lower middle class | 2 (10.00%) | 6 (33.33%) |
| Upper lower class | 15 (75.00%) | 9 (50.00%) |
| Lower class | 1 (5.00%) | 0 (0.00%) |
| Toilet usage | ||
| Flush/pour flush toilet | 19 (95.00%) | 17 (94.44%) |
| Bucket latrine | 1 (5.00%) | 1 (5.56%) |
| Laboratory characteristics | ||
| POG at high vaginal | ||
| At enrolment | 11w3d (9w2d,12w5d)) | 10w4d (7w0d,12w5d) |
| At Visit 2 | 19w4d (18w1d,19w5d) | 19w5d (18w2d,19w6d) |
| At Visit 3 | 26w3d (26w2d,26w4d) | 26w2d (26w1d,26w4d) |
| Birth outcomes | ||
| Normal vaginal | 18 (90.00%) | 17 (94.44%) |
| Caesarean | 2 (10.00%) | 1 (5.56%) |
| Nugent score | ||
| At enrolment | 4 (3,5) | 4 (3,5) |
| At Visit 2 | 4 (3,5) | 4 (3,5) |
| At Visit 3 | 4 (2,5) | 3 (2,4) |
| Vaginal pH at sampling | 5 (5,5) | 5 (5,5) |
| Antibiotic intake at sampling | 0 (0.00%) | 0 (0.00%) |
| Microbial culture result for HVS samples (N=37) | ||
| At enrolment | ||
| Candida species | 2 (10.53%) | 3 (16.67%) |
| Non-pathogenic microbes | 16 (84.21%) | 14 (77.77%) |
| Sterile | 1 (5.26%) | 1 (5.56%) |
| At Visit 2 | ||
| Candida species | 5 (26.31%) | 2 (11.11%) |
| Non-pathogenic microbes | 11 (57.89%) | 13 (72.22%) |
| Sterile | 2 (10.53%) | 3 (16.67%) |
| Escherichia coli | 1 (5.26%) | 0 (0.00%) |
| At Visit 3 | ||
| Candida species | 3 (15.00%) | 0 (0.00%) |
| Non-pathogenic microbes | 13 (65.00%) | 12 (70.59%) |
| Sterile | 4 (20.00%) | 5 (29.41%) |