REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
c-Fos (9F6) Rabbit mAb	Cell Signaling Technology	Cat# 2250, RRID:AB_2247211
GFP Polyclonal Antibody	Thermo Fisher Scientific	Cat# A-11122, RRID:AB_221569
Living Colors® mCherry Monoclonal Antibody	Takara Bio	Cat# 632543, RRID:AB_2307319
Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody	Thermo Fisher Scientific	Cat# A-21206, RRID:AB_2535792
Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 594	Thermo Fisher Scientific	Cat# A-21203, RRID:AB_141633
CaMKII beta Monoclonal Antibody (CB-beta-1)	Thermo Fisher Scientific	Cat# 13-9800, RRID:AB_2533045
Phospho-CaMKII (Thr286) (D21E4) Rabbit mAb antibody	Cell Signaling Technology	Cat# 12716, RRID:AB_2713889
CaMKIIalpha (6G9) antibody	Santa Cruz Biotechnology	Cat# sc-32288, RRID:AB_626787
Anti-GluR1-NT (NT) Antibody, clone RH95	Millipore	Cat# MAB2263, RRID:AB_11212678
Anti-Glutamate Receptor 2, extracellular, clone 6C4 antibody	Millipore	Cat# MAB397, RRID:AB_2113875
AMPA Receptor (GluR 3) (D47E3) Rabbit mAb antibody	Cell Signaling Technology	Cat# 4676, RRID:AB_10547136
Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal	Millipore	Cat# 04-823, RRID:AB_1977218
Anti-α-Tubulin antibody	Sigma-Aldrich	Cat# T9026, RRID:AB_477593
Rabbit Anti-PSD95 Polyclonal Antibody	Cell Signaling Technology	Cat# 2507, RRID:AB_561221
Mouse Anti-Synaptophysin Monoclonal antibody	Millipore	Cat# MAB5258-50UG, RRID:AB_95187
Rabbit Anti-Synapsin II Monoclonal Antibody	Abcam	Cat# ab76494, RRID:AB_2200420
Anti-Histone H4 antibody	Millipore	Cat# 07-108, RRID:AB_2279758
Anti-GM130 (C-terminal) antibody produced in rabbit	Sigma-Aldrich	Cat# G7295, RRID:AB_532244
Anti-β-Actin Antibody	Sigma-Aldrich	Cat# A5441, RRID:AB_476744
Anti-TARPγ-8 antibodt	Park et al. (2016) Sumioka et al. (2011)	N/A
Anti-phospho-TARPγ8 S277 antibody	Park et al. (2016) Sumioka et al. (2011)	N/A
Anti-mouse IgG, HRP-linked Antibody	Cell Signaling Technology	Cat# 7076, RRID:AB_330924
Anti-rabbit IgG, HRP-linked Antibody	Cell Signaling Technology	Cat# 7074, RRID:AB_2099233
AMPA Receptor 1 (GluA1) (D4N9V) antibody	Cell Signaling Technology	Cat# 13185, RRID:AB_2732897
Anti-rabbit IgG (Conformation Specific) (L27A9) mAb (HRP Conjugate) antibody	Cell Signaling Technology	Cat# 5127, RRID:AB_10892860
Bacterial and virus strains
AAV8-Camk2a-GFP	Higuchi et al. (2016)	N/A
AAV8-Camk2a-CaMKIIβ	This paper	N/A
AAV8-Camk2a-CaMKIIβ-CA	This paper	N/A
AAV8-Camk2a-CaMKIIβ-DN	This paper	N/A
AAV9-CMV-GFP-U6-shControl	Vector Biolabs	N/A
AAV9-CMV-GFP-U6-shCaMKIIβ	Vector Biolabs	N/A
AAV8-Camk2a-CaMKIIβ-CARes	This paper	N/A
AAV8-Camk2a-mCherry	This paper	N/A
AAV8-Camk2a-GluA1CT-T2A-mCherry	This paper	N/A
AAV8-Camk2a-GluA1CT-T2A-EGFP	This paper	N/A
AAV8-Camk2a-TARPγ-8D/D-T2A-mCherry	This paper	N/A
Chemicals, peptides, and recombinant proteins
Imipramine	Sigma	I7379
Fluoxetine	FujiFilm Wako	062-05681
Doxycycline	Sigma	D9891
CX614	Tocris	5149
Hydroxypropyl-β-cyclodextrin	Sigma	332607
Hydroxypropyl methylcellulose	Sigma	09963
JNJ-55511118	Tocris	5666
DAPI	Sigma	D9542
TRIzol Reagent	Thermo Fisher Scientific	15596026
Protein G Dynabeads	Thermo Fisher Scientific	10004D
Critical commercial assays
SYBR green PCR Master Mix	Thermo Fisher Scientific	4334973
Direct-zol RNA Miniprep Plus	Zymo research	R2072
RNAscope Fluorescent Multiplex 2.0 assay	Advanced Cell Diagnostics	320850
Pierce 660nm Protein Assay Reagent	Thermo Fisher Scientific	22662
KOD Plus Mutagenesis kit	TOYOBO	SDMK-101
FD Rapid Golgi Stain kit	FD NeuroTechnologies	PK401
Deposited data
Original images of the Western blots	This paper	Mendeley Data, https://doi.org/10.17632/m8zyb8mmtg.1
Experimental models: organisms/strains
Mouse: C57BL/6J	Charles River	RRID: IMSR_JAX:000664
Mouse: BALB/c	Charles River	RRID:MGI:6323059
Mouse: CD1	Charles River	RRID:IMSR_CRL:022
Mouse: C3H	Charles River	RRID:IMSR_CRL:025
Oligonucleotides
Real-time PCR primers	This paper	See Table S1
Recombinant DNA
pAAV-CMV-MCS	Higuchi et al. (2016)	N/A
pAAV-Camk2a-MCS	Higuchi et al. (2016)	N/A
pAAV-Camk2a-GFP	Higuchi et al. (2016)	N/A
pAAV-SYP1-miniSOG-T2A-mCherry vectors	Lin et al. (2013)	Addgene #50972
pEGFPC1-GluR1Ctail	Rumpel et al. (2005)	Addgene #32441
pAAV-Camk2a-CaMKIIβ	This paper	N/A
pAAV-Camk2a-CaMKIIβ-CA	This paper	N/A
pAAV-Camk2a-CaMKIIβ-DN	This paper	N/A
pAAV-CMV-GFP-U6-shControl	Vector Biolabs	N/A
pAAV-CMV-GFP-U6-shCaMKIIβ	Vector Biolabs	N/A
pAAV-Camk2a-CaMKIIβ-CARes	This paper	N/A
pAAV-Camk2a-mCherry	This paper	N/A
pAAV-Camk2a-GluA1CT-T2A-mCherry	This paper	N/A
pAAV-Camk2a-GluA1CT-T2A-EGFP	This paper	N/A
pAAV-Camk2a-TARPγ-8D/D-T2A-mCherry	This paper	N/A
Software and algorithms
GraphPad Prism 7	GraphPad Software	RRID:SCR_002798
ImageJ	NIH	RRID:SCR_003073
Excel	Microsoft	RRID:SCR_016137
Photoshop CS6	Adobe	RRID: SCR_014199
Any-maze	Stoeling	RRID:SCR_014289
BZ-X800 analyzer	Keyence	https://www.keyence.com/
ImageStudio software	LI-COR Biosciences	RRID:SCR_013715
Other
RNAscope probe: Cacng8	Advanced Cell Diagnostics	cat#556161-C1
RNAscope probe: Camk2b	Advanced Cell Diagnostics	cat#453601-C2