Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 19;9:669285. doi: 10.3389/fcell.2021.669285

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xie, Yuan, Huang, Zhang, Zhou, Li and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comprehensive analysis of DCBLD2 mediated 5-FU resistance in CRC. (A) Strategies (Venn diagram) of screening 5-FU resistance-related genes in GDSC, GDC and GEO databases. (B) Results of screening 5-FU resistance-related genes in GDSC, GDC and GEO databases. Ranking of 16 candidate genes based on the sum of the significance of expression differences in the three data sets. (C) The effect of DCBLD2 expression on IC50 value of solid tumor cells was analyzed by GDSC database (***p < 0.001). (D,E) The effect of differential expression of DCBLD2 on overall survival of patients (Kaplan-Meier analysis) was analyzed using TCGA colon cancer data treated with 5-FU (D) and GSE17536 dataset (E).