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. 2021 May 19;11:644885. doi: 10.3389/fonc.2021.644885

Table 1.

Characteristics of men with low-risk prostate cancer in each US census region between 2010 and 2016.

West (n = 29,320) Northeast (n = 12,428) South (n = 14,399) Midwest (n = 4,633) P-value
Median age, years (IQR) 63.0 (57.0–68.0) 63.0 (57.0–68.0) 63.0 (57.0–68.0) 62.0 (57.0–68.0) <0.001
Age, n (%) <0.001
    <60 years 10,067 (34.3%) 4,311 (34.7%) 5,062 (35.2%) 1,730 (37.3%)
    60–69 years 14,373 (49.0%) 5,706 (45.9%) 6,762 (47.0%) 2,110 (45.5%)
    ≥70 years 4,880 (16.6%) 2,411 (19.4%) 2,575 (17.9%) 793 (17.1%)
Year, n (%) <0.001
    2010–2012 16,095 (54.9%) 6,467 (52.0%) 7,388 (51.3%) 2,582 (55.7%)
    2013–2015 10,269 (35.0%) 4,493 (36.2%) 5,434 (37.3%) 1,576 (34.0%)
    2016 2,956 (10.1%) 1,468 (11.8%) 1,577 (11.0%) 475 (10.3%)
Race, n (%) <0.001
    White 23,631 (80.6%) 10,192 (82.0%) 10,343 (71.8%) 3,743 (80.8%)
    Black 2,659 (9.1%) 1,620 (13.0%) 3,910 (27.2%) 810 (17.5%)
    Other/Unknown 3,030 (10.3%) 616 (5.0%) 146 (1.0%) 80 (1.7%)
Median PSA, ng/mL (IQR) 5.5 (4.5–7.0) 5.0 (4.1–6.3) 5.2 (4.3–6.6) 5.2 (4.2–6.6) <0.001
Number of positive cores <0.001
    2 or less positive cores 13,927 (47.5%) 5,793 (46.6%) 6,698 (46.5%) 2,521 (54.4%)
    3 or more positive cores 9,952 (33.9%) 3,399 (27.4%) 4,653 (32.3%) 1,424 (30.7%)
    Unknown 5,441 (18.6%) 3,236 (26.0%) 3,048 (21.2%) 688 (14.9%)
Socioeconomic status, n (%) <0.001
    High SES 16,597 (56.6%) 10,814 (87.0%) 3,628 (25.2%) 1,593 (34.4%)
    Low SES 12,720 (43.4%) 1,613 (13.0%) 10,771 (74.8%) 3,040 (65.6%)
Insurance, n (%) <0.001
    Insured 27,323 (93.2%) 9,892 (79.6%) 13,159 (91.4%) 4,195 (90.6%)
    Medicaid 1,027 (3.5%) 305 (2.5%) 521 (3.6%) 151 (3.3%)
    Uninsured 174 (0.60%) 181 (1.5%) 187 (1.3%) 40 (0.9%)
    Unknown 796 (2.7%) 2,050 (16.5%) 532 (3.7%) 247 (5.3%)
Treatment, n (%) <0.001
    Active Surveillance 10,693 (36.5%) 3,362 (27.1%) 3,407 (23.6%) 1,377 (29.7%)
    Radical prostatectomy 11,385 (38.8%) 4,393 (35.4%) 5,519 (38.3%) 1,962 (42.4%)
    Radiation therapy 7,242 (24.7%) 4,673 (37.6%) 5,473 (38.0%) 1,294 (27.9%)

IQR, Interquartile range.

Percentages may not add up to 100% due to rounding.