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Combined CARs, Dual-singling CAR and Tandem CAR. (A) Simultaneous or sequential use of 2 or more CAR-T cells treating a similar malignant tumor; (B) Dual-signaling CAR refers to the simultaneous and separate expression of 2 different CARs on similar T cell surface; (C) Two different scFvs are connected hand in hand to form tandem CAR on the surface of the T cell.
