Fig. 5. Evaluation of AEAR on cytotoxic T lymphocyte responses. CFSE-labelled target cells from naive mice were injected into the immunized mice after the vaccination. In 4 h after the injection, splenocytes were analyzed to acquire the ratio changes by FACS. (A) Cell populations indicating the changes of CFSE^high and CFSE^low in CFSE-labelled cells. (B) The percentage of specific lysed cells was determined for each group. The values are shown as means ± SE (n = 5). Significant differences relative to FMDV groups were designated.

FMDV, foot-and-mouth disease virus; AEAR, aqueous extract from Artemisia rupestris L.; FITC, fluorescein isothiocyanate; CFSE, carboxyfluorescein succinimidyl ester.

^*p < 0.05, ^*p < 0.01.