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. 2021 May 27;22(1):561. doi: 10.3892/ol.2021.12822

Table VI.

Comparison of the diagnostic value of color Doppler ultrasound, serum CT, serum CEA, and color Doppler ultrasound combined with serum CT and CEA in diagnosing MTC [% (n)].

Detection indices Sensitivity Specificity Accuracy Predictive positive value Predictive negative value
Ultrasound 76.92 (30/39) 96.67 (29/30) 84.06 (58/69) 93.75 (30/32) 75.68 (28/37)
CT 74.36 (29/39) 96.67 (29/30) 84.06 (58/69) 96.67 (29/30) 72.50 (29/40)
CEA 68.23 (27/39) 93.33 (28/30) 78.26 (54/69) 90.00 (27/30) 69.23 (27/39)
Ultrasound combined with CT and CEA 94.87 (37/39)a 93.33 (28/30) 91.30 (63/69) 90.24 (37/41) 92.86 (26/28)
χ2 8.724 0.702 4.490 1.391 5.482
P-value 0.033 0.873 0.213 0.708 0.140
a

P<0.05 vs. the separate ultrasound, serum CT, and serum CEA. CT, calcitonin; CEA, carcinoembryonic antigen; MTC, medullary thyroid carcinoma.