Table 3.
Study | Age (years)/sex | Past medical history | Important labs | Salmonella serotype | Sensitivity | Source of isolate(s) | Abscess size (cm) | Antibiotic therapy | Invasive intervention | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
Rus and Kersnik Levart 10 | 14/male | None | CRP (30 mg/L). ESR (74 mm/h). WBC (15.8 × 109/L). Blood urea nitrogen (44.9 mmol/L). Serum creatinine (425 µmol/L) | S. Enteritidis | [S] ampicillin, ceftriaxone, co-trimoxazole, ciprofloxacin | Urine culture | First scan – size not stated but imaging showed multiple renal abscesses. Second scan (during relapse) – multiple renal abscesses seen (largest 3.3 cm). | First course: Intravenous ceftriaxone for 12 days, followed by oral co-trimoxazole for 9 days. 2nd course: Intravenous ceftriaxone for 4 weeks, followed by oral ciprofloxacin for 2 weeks. | No | Initially cured but had relapse 13 days after initial treatment. Developed arterial hypertension after 6-month follow-up |
Kaur et al 11 | 10/male | Congenital atrophy of left kidney | WBC (16.5 × 109/L). Blood urea (11.8 mmol/L). Serum creatinine (61.9 µmol/L) | S. Typhi | [S] ceftriaxone, cefoperazone-sulbactam, co-trimoxazole, [R] ciprofloxacin | Fluid culture | 4.2 cm × 3.1 cm | Intravenous cefoperazone-sulbactam 1 g TDS for 4 days, followed by 7 days of oral cefixime 200 mg BD. | Aspiration | Cure |
D’Cruz et al 18 | 17/male | None | WBC (3.6 ×109/L) | S. Paratyphi A | [S] ceftriaxone, cefoperazone-sulbactam, ofloxacin, amikacin, gentamicin | Fluid culture | 2.5 × 2.6 cm | Amikacin and ofloxacin for 2 weeks, followed by 2 weeks of ofloxacin monotherapy | Aspiration | Cure |
Our case | 10/female | Nil | CRP (62.5 mg/L). ESR (74 mm/h). WBC (18.23 × 109/L). Blood urea (3.1 mmol/L). Serum creatinine (23 µmol/L) | Group C Salmonella (Salmonella serovar Oranienburg) | [S] ampicillin, ceftriaxone, co-trimoxazole | Fluid culture | 4.2 × 4.0 × 3.1 cm | Intravenous ceftriaxone 100 mg/kg/day for 2 weeks, followed by 4 weeks of oral co-trimoxazole (8 mg/kg/day of trimethoprim twice daily) | Drainage | Cure |
[S], sensitive; [R], resistant.