Table 4.
Provocation/re-exposure to gadolinium contrast media (n = 4 studies).
| Study | Study design | N | Immediate reactions |
Non-immediate reaction |
Culprit skin test negative |
Culprit skin test positive |
Premedication administered prior to
provocation or re-exposure (%) |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Positive SPT or IDT (%) | Positive patch test/SPT and/or IDT (%) | Positive provocation test with culprit or skin test negative alternative GCM (%) | Negative predictive value | Positive provocation with skin test negative GCM (%) | Negative predictive value | Positive provocation with skin test positive GCM | Positive predictive value | ||||
| Chiriac et al. 35 | P | 27 | 5/26 (19.2) | 0/1 (0) | 0/10 (0) | 1 | 0/1 (0) | 1 | – | NA | 3/6 (50) |
| Moulin et al. 36 | P | 1 | 1/1 | – | – | NA | 0/1 (0) | 1 | – | NA | NR |
| Kolenda et al. 37 | R | 33 | 19/33 (57.6) | – | 0/9 (0) | 1 | 0/11 (0) | 1 | – | NA | NR |
| Seta et al. 38 | R, I | 14 | 3/12 (25) | 0/1 (0) | 2/11 (18.2) | 0.82 | 0/1 (0) | 1 | – | NA | NR |
N: number of patients; P: prospective; R: retrospective; I: intervention; NA: not applicable; NR: not reported.