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. 2021 May 19;11:648139. doi: 10.3389/fonc.2021.648139

Table 3.

Summary of adverse events in immune checkpoint inhibition.

Agent Adverse events
Pembrolizumab Arthralgia, Pneumonitis, Hepatotoxicity, Autoimmune hepatitis, Fatigue, Pruritus, Rash, Diarrhea, Colitis, Nausea, Vomiting, Hypothyroidism, Hyperthyroidism
Nivolumab Endocrine toxicities, Pneumonitis, Hepatitis, Diarrhea, Colitis, Fatigue, Pruritus, Nausea
Atezolizumab Fatigue, Hypothyroidism, Nausea, Vomiting, Pruritus, Rash, Diarrhea, Pneumonitis, Arthralgia
Ipilimumab Skin, Gastrointestinal toxicities, Renal toxicities, Autoimmune hepatitis, Fatigue, Diarrhea, Colitis, Nausea, Vomiting, Pneumonitis, Hypothyroidism, Hyperthyroidism, Arthralgia

The major adverse events are depicted in boldface.