Figure 3.

Guideline based treatment of CDI in IBD patients.

^aFor patients who have delayed response to 10-day treatment, the therapy duration should be increased to 14 days.

^bVancomycin taper regimen: VAN 125mg QID for 10–14 days, two times per day for a week, once per day for a week, and then every 2 or 3 days for 2–8 weeks.

^*Strong strength of recommendation.

BID, 2 times a day; CDI, Clostridioides difficile infection; FDX, fidaxomicin; IBD, irritable bowel disease; MNZ, metronidazole; QID, 4 times a day; TID, 3 times a day; VAN, vancomycin.