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. 2021 May 19;11:661431. doi: 10.3389/fonc.2021.661431

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Copyright © 2021 Jiang, Deng, Zhu, Zeng, Hu, Zhou, Xie, Zhang, Fu, Zhou and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LINC00467 promotes the growth of prostate cancer tumors in vivo. (A) Subcutaneous administration of DU145 cells stably transfected with shLINC00467 or control vector into nude mice. (n = six per group). (B) Image illustrating xenograft tumor formation in nude mice. (C, D) The rate of tumor growth and weight were markedly reduced in the shLINC00467 group. (E) RT-qPCR analysis indicating the LINC00467 and miR-494-3p levels in tumor tissues. (F) HE and IHC staining indicating the expression of Ki67 and STAT3 in tumor tissues. **p < 0.01, ***p < 0.001; the data are presented as the means ± SD, n = 3.