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. 2021 May 19;11:574774. doi: 10.3389/fonc.2021.574774

Table 3.

Clinicopathological characteristics and univariate analysis of PTMC patients (n=232).

Small-volume (n=210) Large-volume (n=22) p-value
Gender 0.028*
 Male 74 13
 Female 136 9
Age 0.184
 <45 122 16
 ≥45 88 6
Bilateral tumors 0.292
 Bilateral 46 7
 Unilateral 164 15
Multifocal tumor 0.043*
 Multifocal 61 11
 single 149 11
Hashimoto’s thyroiditis 0.964
 Yes 39 4
 No 171 18
Nodule 0.226
Goiter
 Yes 53 3
 No 157 19
Margin 0.748
 Irregular 179 20
 Regular 31 2
Shape 1.00
 Well-defined 30 3
 Non-well-defined 180 19
Marked Hypoechoic 0.115
 Yes 173 21
 No 37 1
Invasion 0.004*
 Yes 40 12
 No 170 10
ETE** 0.079
 Yes 28 6
 No 182 16
Size of tumors 0.916
 >0.5 136 14
 ≤0.5 74 8

*statistically significance; **extrathyroidal extension.