Fig. 1.

Analysis of differentially expressed long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs). (A) Overview of the workflow of the intersectional network analysis. (B, C and D) Identification of differentially expressed lncRNAs and mRNAs in the hippocampus of depression-susceptible (B), anxiety-susceptible (C) and insusceptible (D) groups. Volcano plot showing variations in gene expression. The fold change log (base 2) is on the x-axis, and the negative false log discovery rate (FDR) (base 10) is on the y-axis. Red signifies high relative expression, and blue signifies low relative expression. Dep-Sus, depression-susceptible; Anx-Sus, anxiety-susceptible; Insus, insusceptible; Cont, control. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)