Fig. 2.

Intergroup analysis of differentially expressed long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs). (A) Venn diagram illustrating the number of altered lncRNAs and mRNAs in the three groups. (B, C and D) Heatmap of differentially expressed lncRNAs and mRNAs based on hierarchical clustering in the depression-susceptible (D1-4), anxiety-susceptible (A1-4) and Insusceptible (I1-4) groups with respect to control (C1-4) (n = 4 per group). Red signifies high relative expression, and blue signifies low relative expression. Color intensity represents expression level, which is noted in the key bar with a log2-scale. Dep-Sus, depression-susceptible; Anx-Sus, anxiety-susceptible; Insus, insusceptible; Cont, control. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)