Analysis of drug-associated messenger RNAs (mRNAs) and long noncoding RNAs (lncRNAs). According to the designed workflow (A), differential mRNAs and correlated lncRNAs from the depression-susceptible (Dep-Sus, B), anxiety-susceptible (Anx-Sus, C) and insusceptible (Insus, D) groups were screened as primary and secondary targets of anti-depression/anxiety drugs. The obtained mRNAs and lncRNAs were then used to construct drug-associated networks and subnetworks.