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. 2021 May 24;44:102014. doi: 10.1016/j.redox.2021.102014

Table 1.

Vimentin modification sites identified in SIN-1 treated and untreated cardiac cells. * Indicates modifications via Schiff base formation.

AA #modified #modifications modified residues modifications
Arg 1 1 R158d dGlutamic semialdehyde
Cys 1 7 C328bcefghi bDioxidation, cTrioxidation, eGlutathionylation, fGlyoxal, gHexenal, hNitrosation, iPentenal
His 5 3 H238g, H253g, H437gj, H461ag, H462ag aOxidation, gHexenal, jHNE
Lys 20 12 K97gjm, K104m, K120m, K129gkmnors, K139gmq, K143glm, K188gm, K223gkmq, K235gjmq, K236glmq, K262g, K282gm, K292gm, K294gm, K313m, K334p, K373gim, K402gm, K439gm, K445gjlm kAcetylation, lDimethylation, mFormylation, nGlyoxal*, gHexenal, oHHE*, jHNE, pMethylation, qMethylglyoxal/MDA, iPentenal, rOxo-pentanal*, sSuccinylation
Met 10 2 M14a, M74a, M154ab, M183ab, M193a, M344ab, M347ab, M372ab, M376ab, M391a aOxidation, bDioxidation
Phe 2 1 F295a, F351a aOxidation
Pro 1 3 P57abt aOxidation, bDioxidation, tPyroglutamic acid
Ser 10 1 S25u, S39u, S49u, S56u, S66u, S83u, S144u, S226u, S430u, S459u uPhosphorylation
Thr 4 2 T37u, T327v, T426v, T458uv v2-amino-3-ketobutyric acid, uPhosphorylation
Trp 1 6 W290abcwxy aOxidation, bDioxidation, cTrioxidation, wHydroxykynurenine, xKynurenine, yOxolactone
Tyr 6 5 Y38auz, Y53abz, Y61abz+, Y150a, Y291abz, Y400a aOxidation, bDioxidation, zDopaquinone, +Nitration, uPhosphorylation