Table 2.
Peak plasma values from laboratory data during ICU stay and comparison between patients with and without VTE
| Laboratory data | Total (n = 56) | No VTE (n = 48) | VTE (DVT ± PE; n = 3, PE n = 5) |
p-value |
|---|---|---|---|---|
| D-dimer, mg/L (IQR) | 3.3 (1.7–8.1) | 2.8 (1.7–7.2) | 24.0 (14.2–50.5) | 0.004 |
| CRP, mg/L (SD) | 296 (108) | 285 (108) | 363 (80) | 0.033 |
| Ferritin, μg/L (IQR) | 2879 (1643–4617) | 2781 (1643–4421) | 3916 (2369–7537) | 0.262 |
| IL-6, ng/L (IQR) | 207 (100–334) | 193 (91–274) | 302 (197–639) | 0.096 |
| Creatinine, μmol/L (IQR) | 95 (78–146) | 94 (78–131) | 288 (131–328) | 0.009 |
| Troponin I, ng/L (IQR) | 21 [10–93] | 21 (10–76) | 79 (20–172) | 0.167 |
| NT-pro-BNP, ng/L (IQR) | 1135 (424–3603) | 937 (406–3203) | 3700 (1003–5630) | 0.167 |
Data are presented as mean (standard deviation) or median (interquartile range). VTE: Venous thromboembolism, DVT: Deep vein thrombosis, CRP: C-reactive protein, IL-6: Interleukin 6, NT-pro-BNP: N-Terminal pro brain natriuretic peptide. Laboratory reference ranges: CRP < 5 mg/L; D-dimer < 0,50 mg/L (non-age-adjusted); Ferritin male patients 25–310 μg/L, female patients 10–155 μg/L (non-age-adjusted); IL-6 < 7,0 ng/L; plasma creatinine male patients 60–105 μmol/L, female patients 45–90 μmol/L; NT-pro-BNP male patients < 230 ng/L, female patients < 330 ng/L (non-age-adjusted); Troponin I male patients < 35 ng/L, female patients < 16 ng/L