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The adipose tissue phenotypes of Nfe2l1(f)-KO mice and Nfe2l1-Floxed control mice under different treatment conditions.
| Genotype | Phenotype | Treatment |
||
|---|---|---|---|---|
| Veh | RGZ | CL316243 | ||
| Nfe2l1-Floxed | Lipolysis | – | – | ↑ |
| Lipogenesis | – | ↑ | – | |
| Hypertrophy | – | – | ↓ | |
| Inflammation |
– |
↓ |
– |
|
| Nfe2l1(f)-KO | Lipolysis | ↓ | ↓ | ↑ |
| Lipogenesis | – | ↑ | – | |
| Hypertrophy | ↑↑ | ↑↑↑ | ↑ | |
| Inflammation | ↑↑ | ↑↑↑ | ↑ | |
↑, increase; ↓, reduce; —, comparable.
