Table 1.
Demographic and ocular parameters of the study population.
| Eye sets | Age (years), mean (SD, range) |
Gender (male), n (%) |
Axial length (mm), mean (SD, range) |
Disc-fovea distance (mm), mean (SD, range) |
Disc-fovea angle (°), mean (SD, range) |
Mean RNFLTa (µm), mean (SD, range) |
||
| All (n=2731) | 63.0 (9.2, 50 to 91) |
1214 (44.5) |
23.23 (1.01, 18.96 to 28.87) | 4.93 (0.39, 3.68 to 7.63) | 7.64 (3.51, –16.64 to 23.25) |
101 (12, 32 to 147) | ||
| Normal (n=2477) | 62.3 (8.9, 50 to 91) |
1076 (43.4) |
23.18 (0.96, 18.96 to 28.87) |
4.88 (0.27, 3.68 to 5.99) |
7.59 (3.4, –16.64 to 23.25) |
102 (11, 43 to 147) |
||
| Glaucoma (n=254) | 69.4 (9.3, 50 to 90) |
138 (54.3) |
23.77 (1.27, 19.59 to 28.84) |
5.41 (0.82, 3.8 to 7.63) |
8.16 (4.36, –13.14 to 22.59) | 85 (17, 33 to 122) |
||
| Training set |
|
|
|
|
|
|
||
|
|
All eyes (n=2223) | 62.2 (8.9, 50 to 91) |
960 (43.2) |
23.16 (0.96, 18.96 to 28.87) |
4.88 (0.27, 3.68 to 5.99) |
7.67 (3.42, –16.64 to 23.25) |
102 (11, 43 to 141) |
|
|
|
10% longest eyes (n=222) | 63.5 (8.7, 50 to 85) |
145 (65.3) |
25.08 (0.77, 24.32 to 28.78) |
4.86 (0.3, 3.86 to 5.99) |
7.49 (3.86, –6.3 to 23.25) |
96 (10, 60 to 119) |
|
|
|
20% longest eyes (n=444) | 63.41 (8.77, 50 to 85) |
290 (65.3) |
24.56 (0.76, 23.83 to 28.87) |
4.83 (0.28, 3.68 to 5.99) |
7.64 (3.55, –6.3 to 23.25) |
98 (11, 43 to 124) |
|
|
|
30% longest eyes (n=666) | 63.3 (8.97, 50 to 90) |
408 (61.2) |
24.26 (0.75, 23.53 to 28.87) |
4.84 (0.27, 3.68 to 5.99) |
7.62 (3.4, –6.3 to 23.25) |
100 (11, 43 to 139) |
|
| Validation set |
|
|
|
|
|
|
||
|
|
All eyes n=508) | 66.4 (9.6, 50 to 90) |
254 (50. 0) |
23.53 (1.15, 19.59 to 28.84) |
5.14 (0.67, 3.8 to 7.63) |
7.54 (3.87, –13.14 to 22.59) |
94 (17, 32 to 147) |
|
|
|
Glaucoma in all eyes (n=254) | 69.4 (9.3, 50 to 90) |
138 (54.3) |
23.77 (1.28, 19.59 to 28.84) |
5.41 (0.82, 3.8 to 7.63) |
8.16 (4.37, –13.14 to 22.59) |
86 (17, 32 to 122) |
|
|
|
10% longest eyes (n=51) | 68.3 (9.3, 50 to 90) |
32 (62.7) |
26.01 (0.89, 24.95 to 28.84) |
5.3 (0.9, 4.05 to 7.63) |
8.44 (4.39, –2.05 to 22.59) |
82 (16, 40 to 122) |
|
|
|
Glaucoma in 10% longest eyes (n=37) | 68.78 (9.8, 50 to 90) |
23 (62.2) |
26.2 (0.93, 24.95 to 28.84) |
5.46 (0.99, 4.05 to 7.63) |
8.88 (4.92, –2.05 to 22.59) |
80 (17, 40 to 122) |
|
|
|
20% longest eyes (n=102) | 67.8 (9.2, 50 to 90) |
66 (64.7) |
25.26 (0.99, 24.21 to 28.84) |
5.34 (0.85, (4.05 to 7.63) |
7.92 (3.99, –2.05 to 22.59) |
88 (17, 38 to 122) |
|
|
|
Glaucoma in 20% longest eyes (n=66) | 68.1 (9.2, 50 to 90) |
41 (62.1) |
25.44 (1.08, 24.21 to 28.84) |
5.58 (0.95, 4.05 to 7.63) |
8.5 (4.43, –2.05 to 22.59) |
83 (17, 38 to 122) |
|
|
|
30% longest eyes (n=153) | 67.2 (9.0, 50 to 90) |
99 (64.7) |
24.86 (0.99, 23.92 to 28.84) |
5.27 (0.77, 3.8 to 7.63) |
7.51 (4.18 (–13.14 to 22.59) |
90 (17, 38 to 147) |
|
|
|
Glaucoma in 30% longest eyes (n=91) | 67.8 (9.0, 50 to 90) |
57 (62.6) |
25.06 (1.11, 23.92 to 28.84) |
5.5 (0.9, 3.8 to 7.63) |
7.91 (4.79, –13.14 to 22.59) |
85 (17, 38 to 122) |
|
aRNFLT: retinal nerve fiber layer thickness.