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. 2021 Jun 2;26(7-8):415–430. doi: 10.1007/s10495-021-01680-2

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© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Fig. 3 — Photomicrograph of the testis stained with H&E; (× 4, × 10 and × 40). SG Spermatogonia (SG), primary spermatocyte (PS), round spermatid (ST), Sertoli cell (SC), Leydig cell (LC). A In the control group, the testis tissue, including the seminiferous tubules and germinal epithelium, has a normal appearance. B The testicular cells death, interstitial edema and thinning of the seminiferous epithelium was observed in all autopsy COVID-19 specimens of testes. C A point grid is superimposed over the photomicrograph for measuring the volume using Cavalieri method. D Counting frames are superimposed over the photomicrographs to measure the number of testicular cells using optical disector method. The yellow box is counting frame (Color figure online)