PDGF-BB inhibits miR-125b expression in VSMCs. (A) Treatment with PDGF-BB decreases miR-125b expression, the effects of which are reversed following transfection of A10 cells with miR-125b mimic. (B) Treatment with PDGF-BB decreases miR-125b expression, the effects of which are reversed following transfection of A10 cells with miR-125b inhibitor. Data are presented as the mean ± standard deviation. One-way analysis of variance and the Tukey's post hoc test were used. *P<0.05, ***P<0.001. PDGF-BB, platelet-derived growth factor-BB; miR, microRNA; VSMCs, vascular smooth muscle cells; NC, negative control.