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(A) a flow cytometry gate AML- EVs. Flow-cytometric analyses showed that the AML-EVs express CD63, CD9, CD33 CD34, and HLA DR (b, c, d, e, and f). (B) Measurement of the size range of EVs by DLS with the average size of 340 nm. (C, D, and E) TEM analyses of EVs, three groups of newly diagnosed patients, healthy subjects and relapsed patients, respectively
