Table 1.
The demographics and clinical characteristic of TM bloodstream infection AIDS patients
| Demographics and clinical data | Normal range | Total cases (n = 87) | Survival cases (n = 72) | Poor prognosis (n = 15) | P-value |
|---|---|---|---|---|---|
| Age (years) | – | 34.0 (28.0--44.0) | 33.5 (27.3--43.0) | 37.0 (30.0—46.0) | 0.71 |
| Male (%) | – | 81 (93%) | 68 (94%) | 13 (87%) | 0.28* |
| WBC (*10^9/L) | 3.5 ~ 9.5 | 3.4 (2.4--5.1) | 3.4 (2.4--4.9) | 4.5 (2.1—8.1) | 0.57 |
| Neutrophil (*10^9/L) | 1.8 ~ 6.3 | 2.9 (1.7--4.2) | 2.9 (1.7--4.0) | 2.4 (1.6—6.5) | 0.65 |
| Hemoglobin (g/L) | 115 ~ 150 | 94 (81--107) | 95 (81--107) | 86 (80—104) | 0.30 |
| Platelet (*10^9/L) | 125 ~ 350 | 100 (66--155) | 99.5 (72.3--149.3) | 103 (23—198) | 0.60 |
| CD4 count (/ul) | 410 ~ 1590 |
7 (4--19) N† = 84 |
9 (4--21) N† = 71 |
5 (3—12) N† = 13 |
0.05 |
| CD8 count (/ul) | 190 ~ 1140 | 202 (98--336) N = 82 |
223 (106--384) N = 70 |
122 (57—186) N = 12 |
0.01 |
| Ratio of CD4/CD8 | 0.9 ~ 3.6 | 0.04 (0.02--0.10) N = 82 |
0.04 (0.02--0.10) N = 70 |
0.06 (0.03—0.10) N = 12 |
0.74 |
| BUN (mmol/L) | 2.6 ~ 7.5 | 4.1 (3.2--6.0) N = 86 |
4.0 (3.1--5.4) N = 72 |
6.6 (4.0—12.2) N = 14 |
0.001 |
| Serum Albumin (g/L) | 40 ~ 55 |
27 (23--31) N = 86 |
28 (24--31) N = 72 |
25 (22—28) N = 14 |
0.07 |
| PCT (ng/mL) | 0 ~ 0.05 | 0.63 (0.21--1.75) N = 74 | 0.50 (0.19--1.65) N = 63 | 1.09 (0.62—15.45) N = 11 | 0.04 |
| CRP (mg/L) | 0 ~ 10 |
54 (26--88) N = 76 |
44 (24--81) N = 63 |
71 (53—111) N = 13 |
0.03 |
| BDG (pg/mL) | < 60 | 194 (48--264) N = 74 |
205 (101--287) N = 62 |
54 (10—222) N = 12 |
0.01 |
| Fever | – | 81 (93.1%) | 67 (93.1%) | 14 (93.3%) | 0.97* |
| Rash | – | 31 (35.6%) | 26 (36.1%) | 5 (33.3%) | 0.84* |
| Lymphnode enlargement | – | 25 (28.7%) | 21 (29.2%) | 4 (26.7%) | 0.85* |
| TB coinfection | – | 5 (5.7%) | 5(6.9%) | 0(0%) | 0.29* |
| NTM disease | – | 10(11.5%) | 9 (12.5%) | 1 (6.7%) | 0.52* |
| CMVR | – | 8 (9.2%) | 8 (11.1%) | 0 (0%) | 0.18* |
| PCP | – | 10 (11.5%) | 8(11.1%) | 2 (13.3%) | 0.81* |
| Cryptococcal meningitis | – | 1 (1.1%) | 1 (1.4%) | 0(0%) | 0.65* |
| Oral candidiasis | – | 9 (10.3%) | 5 (6.9%) | 4 (26.7%) | 0.02* |
| Hospital stay (days) | – | 21 (16–25) | 22 (19–26) | 5 (3–13) | < 0.0001 |
| Culture turnaround (days) | – | 8 (6--9) | 8 (6--9) | 6 (5--9) | 0.12 |
* By Fisher exact test; Others by Mann-Whitney test; †N, means some of the cases with the clinical data and being collected in this analysis. WBC white blood cell; BUN blood urea nitrogen; PCT procalcitonin; CRP C-reactive protein; BDG 1,3-β-D-Glucose; TB tuberculosis; NTM Nontuberculous mycobacteria; CMVR Cytomegalovirus rentinitis; PCP Pneumocystis jirovecii pueumonia