Table 2.

GWAS identified SNPs Associated with Lp(a) Level

SNP	gene	Genomic Coordinate	EA/OA	MAF	HWE(P)	β	SE	P Value
rs1018234	SLC22A3	Chr6: 160375026	T/C	0.3798	0.76208	−0.10526	0.04359	0.0158924620
rs117052562	–	Chr6: 160689582	A/G	0.0510	0.98824	0.34649	0.09508	0.0002792119
rs1406888	–	Chr6: 160670561	C/T	0.4591	0.84080	−0.11589	0.04178	0.0056265889
rs14224	PLG	Chr6: 160716747	C/T	0.4669	0.75426	−0.03305	0.04251	0.4370000000
rs1510224	LPAL2	Chr6: 160473846	C/T	0.0739	0.52604	0.03701	0.08178	0.6509000000
rs2048327	SLC22A3	Chr6: 160442500	C/T	0.4502	0.99758	0.10507	0.04207	0.0126382227
rs2140650	MAP3K4	Chr6: 161087406	G/A	0.3442	0.89826	0.04999	0.04449	0.2614000000
rs2457574	SLC22A3	Chr6: 160447669	G/A	0.4542	0.99196	0.10907	0.04193	0.0094065915
rs2504921	LPAL2	Chr6: 160472974	T/G	0.3637	0.57725	0.07793	0.04293	0.0697000000
rs3127599	LPAL2	Chr6: 160486102	T/C	0.1507	0.86040	−0.00228	0.05921	0.9694000000
rs3798220	LPA	Chr6: 160540105	C/T	0.0748	0.92082	0.0249	0.08039	0.7568000000
rs41269133	–	Chr6: 160666831	C/T	0.2293	0.98939	−0.54028	0.04781	2.92E-28
rs429358	APOE	Chr19: 44908684	C/T	0.0829	0.97570	−0.19333	0.07645	0.0115732887
rs505151	PCSK9	Chr1: 55063514	G/A	0.0717	0.98202	0.10972	0.08146	0.1783000000
rs520829	SLC22A3	Chr6: 160346873	G/T	0.3157	0.72279	−0.11847	0.04555	0.0094079135
rs56393506	–	Chr6: 160668275	T/C	0.1778	0.81177	0.71204	0.05135	9.08E-41
rs5925	LDLR	Chr19: 11120205	C/T	0.2178	0.36628	0.07037	0.05181	0.1746000000
rs5927	LDLR	Chr19: 11123265	A/G	0.0518	0.93586	−0.09713	0.09432	0.3033000000
rs5929	LDLR	Chr19: 11116124	T/C	0.3062	0.97795	−0.01452	0.04569	0.7506000000
rs5930	LDLR	Chr19: 11113589	A/G	0.3665	0.16534	−0.08394	0.04471	0.0607000000
rs6415084	LPA	Chr6: 160559298	T/C	0.1663	0.67734	0.62622	0.05342	3.51E-30
rs641990	SLC22A3	Chr6: 160358102	A/G	0.3945	0.58243	−0.07539	0.04388	0.0860000000
rs662145	PCSK9	Chr1: 55064155	C/T	0.1231	0.03321	0.12342	0.06155	0.0451562913
rs688	LDLR	Chr19: 11116926	T/C	0.1618	0.72698	0.05544	0.05762	0.3362000000
rs7412	APOE	Chr19: 44908822	T/C	0.0809	0.15342	−0.14293	0.07983	0.0736000000
rs7765781	LPA	Chr6: 160586464	C/G	0.4021	0.17321	−0.41375	0.04012	5.45E-24
rs7770628	LPA	Chr6: 160597142	C/T	0.1835	0.95012	0.70012	0.05102	5.09E-40
rs783147	PLG	Chr6: 160716958	G/A	0.4980	0.51151	−0.0018	0.04264	0.9664000000
rs9457778	–	Chr6: 159932259	C/T	0.3705	0.22391	0.09361	0.04241	0.0274770059

SNP single nucleotide polymorphism, EA/OA effect allele/ other allele, MAF minor allele frequency, HWE(P) P value of Hardy-Weinberg equilibrium, SE standard error; sex and age were included into models for adjustment