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. 2021 Jun 2;14:75. doi: 10.1186/s13048-021-00821-0

Table 2.

The relationship between BOLA family members and OS in other different subtypes of OC (Kaplan-Meier plotter)

Subtypes BOLA1 BOLA2 BOLA3
Cases HR (95% CI) P value Cases HR (95% CI) P value Cases HR (95% CI) Pvalue
Histology Serous 1207 0.93(0.8–1.08) 0.34 1207 0.86(0.73–1.01) 0.061 523 1.36(1.04–1.77) 0.022
Endometrioid 37 2.13(0.24–19.05) 0.49 37 4.42(0.74–26.51) 0.075 30 3.77(0.39–36.42) 0.22
Stage 1 74 2.29 (0.73–7.25) 0.15 74 0.43 (0.14–1.35) 0.14 51 2.52 (0.6–10.55) 0.19
2 61 0.52 (0.18–1.5) 0.22 61 0.28 (0.08–1.01) 0.038 32 0.16 (0.02–1.36) 0.057
3 1044 1.15 (0.97–1.36) 0.097 1044 1.15 (0.95–1.38) 0.15 426 1.38 (1.05–1.81) 0.019
4 176 1.38 (0.95–2.01) 0.087 176 0.69 (0.47–1.02) 0.059 61 0.49 (0.26–0.9) 0.019
Grade 1 + 2 380 1.54 (1.16–2.06) 0.003 380 0.79 (0.6–1.06) 0.11 203 1.54 (0.97–2.46) 0.064
3 1015 1.11 (0.92–1.34) 0.28 1015 0.82 (0.7–0.98) 0.025 392 0.73 (0.56–0.96) 0.022
TP53 Mutated 506 0.84 (0.65–1.08) 0.17 506 0.71 (0.56–0.89) 0.0025 124 0.79 (0.54–1.16) 0.23
WT 94 0.5 (0.29–0.89) 0.015 94 0.54 (0.25–1.14) 0.1 19 1.38 (0.49–3.92) 0.54
CR Platin 1409 1.14 (0.99–1.32) 0.07 1409 0.94 (0.81–1.09) 0.41 478 1.30 (1–1.69) 0.047
Taxol 793 1.16 (0.95–1.4) 0.14 793 1.17 (0.97–1.41) 0.11 357 1.39 (1.01–1.93) 0.043
Taxol + platin 776 1.17 (0.97–1.43) 0.10 776 1.19 (0.98–1.44) 0.075 356 1.40(1.01–1.93) 0.041

The bold font indicates the difference was significant statistically

OC ovarian cancer, OS overall survival, WT wild type, CR Chemotherapy Regimen