Table 3.
Non-covalent bond distances between M10, SARS-CoV2 Mpro and SARS-CoV.
| Non-covalent bond distances between M10 and SARS-CoV2 Mpro | Distance (Å) | Bonding category | Non-covalent bond distances between M10 and SARS-CoVMpro | Distance (Å) | Bonding category |
|---|---|---|---|---|---|
| A:GLY143:HN - :M10:N18 |
2.566 | Hydrogen bond |
A:HIS163:HE2 - :M10:O1 |
2.042 | Hydrogen bond |
| A:ASP187:HA - :M10:O8 |
2.812 | Hydrogen bond |
:M10:H1 - A:GLU166:OE2 |
2.262 | Hydrogen bond |
| A:GLN189:HA - :M10 |
2.844 | Hydrophobic | A:SER144:HG - :M10:O2 |
2.443 | Hydrogen bond |
| :M10:H28 - A:MET165:SD |
2.919 | Hydrogen bond | A:LEU141:HA - :M10:N3 |
2.721 | Hydrogen bond |
| A:ARG188:HA - :M10:O7 |
3.080 | Hydrogen bond | :M10:H12 - A:CYS44:O |
2.783 | Hydrogen bond |
| :M10:C1 - A:PRO168 | 4.435 | Hydrophobic | :M10:H11 - A:CYS44:O |
3.094 | Hydrogen bond |
| A:HIS41 - :M10 | 4.543 | Hydrophobic | A:CYS145:SG - :M10 | 3.571 | Other |
| :M10 - A:CYS145 | 4.705 | Hydrophobi c | A:LEU141:C,O;ASN142:N - :M10 | 3.725 | Hydrophobic |
| :M10 - A:MET49 | 5.108 | Hydrophobi c | A:MET49:SD - :M10 | 4.889 | Other |
| A:CYS145:SG - :M10 | 5.121 | Other | :M10:S1 -A:HIS163 | 5.054 | Other |
| A:MET165:SD - :M10 | 5.410 | Other | A:HIS41 - :M10 | 5.078 | Hydrophobic |
| :M10: S1 - A: HIS172 | 5.971 | Other |