Table 2A.

ADME properties of the selected twenty compounds.

Drug Name	QPlogPo/w (-2.5 to 6.5)	QPlogS (-6.5 to 0 .5)	QPlogHERG (below -5.0)	QPPCaco (<25%-poor,>500-great)	QPlogBB (-3 to 1.2)	QPPMDCK (<25%-poor,>500-great)	QPlogKp (-8.0 to-0.1)	QPlogKhsa (-1.5 to 1.5)
Anti-inflammatory
Rutin Hydrate	−2.476	−2.624	−5.864	0.895	−4.915	0.251	−7.269	−1.358
Silymarin	1.672	−4.808	−5.924	26.684	−2.636	9.847	−4.911	0.009
Quercetin	0.384	−2.874	−5.088	20.005	−2.367	7.212	−5.457	−0.348
Mitoxantrone 2HCl	0.512	−1.919	−7.66	0.855	−3.088	0.292	−9.085	−0.327
Luteolin	0.963	−3.109	−5.061	41.618	−1.954	15.92	−4.86	−0.188
Aloin	−0.464	−2.896	−5.035	9.05	−3.05	3.06	−5.958	−0.652
Morin Hydrate	0.419	−2.67	−4.853	26.94	−2.158	9.949	−5.206	−0.361
Kaempferol	1.054	−3.056	−5.077	57.783	−1.805	22.699	−4.542	−0.197
Madecassoside	−2.561	−2.203	−5.001	0.586	−5.55	0.159	−7.596	−1.648
Antibiotics
Amikacin Hydrate	−8.684	−0.237	−6.399	0.002	−5.175	0.001	−12.607	−2.555
Geneticin	−5.151	2	−7.209	0.208	−2.481	0.07	−9.781	−1.448
Netilmicin Sulfate	−3.598	2	−8.628	0.556	−2.199	0.203	−8.935	−1.097
Hygromycin B	−5.929	1.997	−6.901	0.047	−3.441	0.014	−10.945	−1.788
Antidiabetic
Acarbose	−6.893	0.846	−4.921	0.128	−4.679	0.034	−9.797	−2.257
Apigenin	1.632	−3.341	−5.126	119.76	−1.428	49.902	−3.942	−0.035
Hesperidin	−1.437	−2.798	−5.425	4.802	−3.926	1.543	−6.139	−1.172
Neohesperidin	−1.128	−4.292	−6.533	3.283	−4.846	1.023	−6.447	−1.174
Troxerutin	−2.526	−2.119	−6.331	0.818	−6.05	0.228	−6.65	−1.939
Notoginsenoside R1	−1.195	−3.123	−5.482	1.138	−5.704	0.325	−6.847	−1.423
Cardiovascular Disease
Salvianolic AcidB	2.25	−5.927	−4.095	0.004	−7.326	0.001	−8.372	−0.397