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. 2021 May 25:1–30. doi: 10.1080/07391102.2021.1913228

Table 11.

Docking Parameters of Top scoring Drugs to target RNA dependent RNA Polymerase from SARS-COV-2 (PDB ID 7BTF).

Drugs GScore DScore Lipophilic EVDW HBond EModel
EKB-569 −8.97 −6.45 −4.4 −2.1 −87.789
Campothecin −7.81 −7.1 −6.5 −0.4 −72.146
Amodiaquine −7.53 −7.53 −5.3 −1.6 −78.285
Primaquine −7.1 −7 −6.2 −2.5 −71.433
Dequalinium −7.04 −6.4 −5.2 −0.7 −78.145
Elvitegravir −7.04 −4.19 −1.92 −1.78 −80.599
Imiquimod −6.7 −6.6 −4 −1.9 −59.016
Saquinavir −6.4 −6.4 −5.8 −2 −87.479
Afatinib −5.9 −4 −5.2 −0.5 −73.441
Acalabrutinib −5.4 −5 −4.3 −0.7 −73.387
Hydroxychloroquine −6.1 −5.11 −4.4 −1.2 −44.626
Remdesivir −8.4 −8.4 −5.6 −2.3 −82.944
Galidesivir −5.4 −5.3 −0.7 −3.3 −42.332