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. 2021 Jun 1;22:165. doi: 10.1186/s12931-021-01753-5

Table 2.

ROC analysis of different indicators in distinguishing ATB from non-TB in suspected patients with positive T-SPOT results

Cutoff value Sensitivity Specificity PLR P value
ESAT-6 sfc  > 20 76.4 76.0 3.2 P < 0.0001
CFP-10 sfc  > 40 66.4 88.7 5.9 P < 0.0001
PHA sfc  < 214 37.3 85.8 2.6 P < 0.0001

ATB including confirmed ATB and probable ATB

ROC receiver operating characteristic, ATB active tuberculosis, ESAT-6 early secreted antigenic target 6, CFP-10 culture filtrate protein 10, PHA phytohaemagglutinin, sfc spot-forming cells