Table 3.
Comparison of patient characteristics between the PD responders and non-PD responders
| PD responders n = 30 |
Non-PD responders n = 29 |
p-value | |
|---|---|---|---|
| Age, yrs | 74 (67–78) | 70 (62–74) | 0.058 |
| Male, n | 8 (26.7) | 8 (27.6) | 1.00 |
| Disease duration, months | 92 (26–258) | 39 (10–156) | 0.071 |
| Positive RF, n | 27 (90.0) | 19 (65.5) | 0.030 |
| Positive ACPA, n | 28 (93.3) | 24 (82.8) | 0.21 |
| SDAI | 25.0 (16.6–36.5) | 18.2 (12.2–24.5) | 0.0081 |
| Total GS score | 19 (13–28) | 8 (4–15) | 0.0005 |
| Total PD score | 11 (7–20) | 4 (1–7) | < 0.0001 |
| Dkk-1, pg/ml | 3040 (2489–3652) | 3699 (2676–4477) | 0.026 |
| SOST, pg/ml | 2428 (1721–3057) | 2803 (2137–3916) | 0.058 |
| OC, pg/ml | 16,588 (9582–28,327) | 17,722 (12512–39,103) | 0.54 |
| OPG, pg/ml | 958 (749–1190) | 945 (839–1534) | 0.32 |
| OPN, pg/ml | 23,035 (17382–40,435) | 22,928 (17305–35,962) | 0.93 |
ACPA Anti-cyclic citrullinated peptide antibody, OC Osteocalcin, OPG Osteoprotegrin, OPN Osteopontin, PD Power Doppler, RF Rheumatoid factor, SDAI Simplified Disease Activity Index, SOST Sclerostin