. Author manuscript; available in PMC: 2021 Jun 2.

Published in final edited form as: Ann Allergy Asthma Immunol. 2020 May;124(5):424–440.e17. doi: 10.1016/j.anai.2020.03.021

Table 7.

Summary of Findings for PICO Question 5c^a

2-Food elimination diet compared to placebo for EoE
Outcomes and follow-up	No. of participants (studies)^67,71	Certainty of the evidence (GRADE)	Relative effect, RR (95% CI)	Anticipated absolute effects
Outcomes and follow-up	No. of participants (studies)^67,71	Certainty of the evidence (GRADE)	Relative effect, RR (95% CI)	Risk with placebo	Risk difference with 2-food elimination diet
Not achieving histologic remission (remission) assessed with <15 eos/hpf, follow-up: 6 wk	311 (2 observational studies)^b,c	⊕◯◯◯ VERY LOW	0.66 (0.57–0.77)	880 per 1000^d	299 fewer per 1000 (378 fewer to 202 fewer)

The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

2-Food elimination diet = milk + wheat (Molina-Infante et al⁶⁷).

2-Food elimination diet = milk + soy (Reed et al⁷¹).

Placebo group is from topical steroid trials.