Table 8.

Summary of Findings for PICO Question 5d^a

Single-food elimination compared to placebo for EoE
Outcomes	No. of participants (studies), follow-up72,73	Certainty of the evidence (GRADE)	Relative effect, RR (95% CI)	Anticipated absolute effects
				Risk with placebo	Risk difference with single-food elimination
Not achieving histologic remission (remission) assessed with <15 eos/hpf, follow-up: 6 wk	203 (2 observational studies)b,c	⊕◯◯◯ VERY LOWd	0.52 (0.37–0.74)	880 per 1000e	422 fewer per 1000 (554 fewer to 229 fewer)

^aThe risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

^bMilk (Kagalwalla et al⁷²).

^cMilk, 6 dropped out and were considered treatment failures for this analysis (Kruszewski et al⁷³).

^dLow information size.

^ePlacebo data are from topical steroid studies.