Figure 4.

In-chip crystallization of γS-crystallin. Crystallization of the γS-crystallin variant using the same crystallization condition in traditional hanging drops (a) and in-chip crystallization (b). The inset shows an enlarged image of a crystal within the chip features. (c) The solved structure of the γS-crystallin variant with two monomers linked via a disulfide bond. (d) Representative section of the 2F _o − F _c electron-density map (contoured at 2σ) after refinement. Chain A is colored from blue to red from the N-terminus to the C-terminus, while chain B is colored from green to cyan.