Figure 5.

In vivo fluorescence images of 4T1-tumor-bearing nude mice at different time points post intravenous injection of HA/DOX@PPy NGs, MAs and MAs-NGs (A). Ex vivo fluorescence images of major organs and tumors (B), and the corresponding tumor/liver fluorescence ratio (C) at 48 h post-injection of HA/DOX@PPy, MAs and MAs-NGs, respectively (** p < 0.01). In vivo thermal images (D) and temperature changes (E) of tumor-bearing nude mice after different treatments when exposed to an 808 nm laser at 1.5 W/cm² for 5 min.