Table 1.

Post-translational modifications of mammalian mitochondrial dynamics-related proteins

Protein substrate	Regulators	Full name	Post-transcriptional modification	Effects of the modifications	References
Drp1	CDK1	Cyclin-dependent kinase 1	Phosphorylation of Ser 616	Activation	184
	PKA	Protein kinase A	Phosphorylation of Ser637	Inactivation	185
	DNA-PKcs	DNA-dependent protein kinase, catalytic subunit	Phosphorylation of Ser616	Activation	186
	O-GlcNAc transferase or OGT	uridine diphospho-N-acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase	O-GlcNAcylation of Drp1 at Thr585/586	Activation	187
	MAPL	Mitochondria-associated protein ligase	SUMOylation of Drp1	Activation	188
	SENP5	SUMO-specific Peptidase 5	De-SUMOylation of Drp1	Inactivation/stabilization	189
	March5	Membrane associated RING finger protein 5	Ubiquitination of Drp1	Degradation	190
Mfn1	ERK	Extracellular-signal-regulated kinase 1/2	Phosphorylation of T562	Inactivation	191
	March5	Membrane associated RING finger protein 5	Ubiquitin of Mfn1	Degradation	192
Mfn2	PINK1	PTEN-induced kinase 1	Phosphorylation of Thr111 and Ser442	Signaling	193
	March5	Membrane associated RING finger protein 5	Ubiquitin of Mfn2	Activation	194
Mfn1/2	USP30	Ubiquitin specific peptidase 30	Deubiquitin of Mfn1/2	Inactivation	195
Mff	NR4A1	Nuclear receptor subfamily 4 group A member 1	Phosphorylation of Ser146	Activation	196