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The Ncom Gel vaccine dramatically enhanced the production of antigen-specific antibodies in vivo. (A) Schematic illustration of immunization and analysis schedule. (B) The titer of anti-OVA IgG antibodies in plasma was detected by ELISA. (C-D) The titers of anti-OVA IgG1 antibodies and anti-OVA IgG2b antibodies in plasma on days 21, 28 and 35 were detected by ELISA (n=3, mean ± SD, * P < 0.05, **P < 0.01, *** P< 0.001 and **** P< 0.0001).
