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CD4+ T cell proliferation assessed by CTV-dilution in fresh PBMC from two HLA-DQ2.5+ CD patients incubated for 8 days with peptide pools containing Nexvax2 peptides (NX), non Nexvax2 peptides (xNX) or both, or CEFT positive control peptides. Mean (SEM) percent proliferating CD4+ T cells (A, B) and mean fold-difference in proliferation compared to control (C, D) is shown for PBMC incubated with peptide mixes, data represent mean of triplicates.
