Table 2.
Overview of studies on the elemental diet.
| Level | Author, publication year | Mean age (years) | n | Period | Duration of diet | PPI | Histological response(eos/HPF) | Remission rate |
|---|---|---|---|---|---|---|---|---|
| A | Markowitz, 2003 | 8,3 (3–16) |
51 | 1997-2000 | 4 weeks | Yes, NR | Reduction | 96% |
| A | Rizo Pascual, 2011 | 9 (2,8–14,5) |
3 | 2001-2009 | 8 weeks | NA | <10 | 100% |
| A | Al Hussaini, 2013 | 1,5 (1–2) |
4 | 2009-2012 | 8 weeks | NA | ≤ 5 | 75% |
| B | Kagalwalla, 2006 | 6,4 | 25 | 2001-2003 | 6 weeks | NR | ≤ 10 | 88% |
| B | Leung, 2015 | 13 (8–18) |
7 | 2007-2013 | 8 weeks | Yes, NR | < 10 | 100% |
| C | Liacouras, 2005 | 8,1 | 164 | 1994-2004 | 4-5 weeks | NR | Reduction | 97% |
| C | Henderson, 2012 | 5,6 (0,9–19,7) |
49 | 1999-2011 | Mean 4.5 months | NR | < 15 | 96% |
| C | Spergel, 2012 | 6,4 (1–18) |
43 | 2000-2011 | NA | NR | ≤ 15 | 98% |
NA, not applicable; PPI, proton pump inhibitors; NR, non-responder; R, responder; eos/HPF, eosinophils per high-power field.
Bolded value: the number of children in the intervention group was not specified, we therefore approached the unknown as stated in the method section “Analysis”.