Table 3.
Overview of studies on the allergy test-directed elimination diet.
| Level | Author, publication year | Mean age (years) | n | Period | Duration of diet | PPI | Allergen evaluation | Histological response(eos/HPF) | Remission rate |
|---|---|---|---|---|---|---|---|---|---|
| A | Rizo Pascual, 2011 | 9 (2,8–14,5) |
12 | 2001-2009 | 8 weeks | NA | SPT, APT & Immunocap |
< 10 | 42% |
| A | Al Hussaini, 2013 | 6,8 (4–11) |
10 | 2009-2012 | 8 weeks | NA | SPT & Immunocap |
< 15 | 40% |
| A | TE Gómez, 2019 | 10,4 (5–15) |
22 | 2011-2016 | 6 weeks | NA | Immunocap | < 15 | 77% |
| C | Liacouras, 2005 | 10,4 | 132 | 1994-2004 | 4-5 weeks | NR | SPT & APT | Reduction | 57% |
| C | Henderson, 2012 | 5,2 (0,9–15,0) |
23 | 1999-2011 | Mean 3,9 months | NR | SPT & APT | < 15 | 65% |
| C | Spergel, 2012 | 6,4 (1–18) |
40 | 2000-2011 | NA | NR | SPT & APT | ≤ 15 | 53% |
NA, not applicable; PPI, proton pump inhibitors; NR, non-responder; R, responder; eos/HPF, eosinophils per high-power field; SPT, skin prick test; APT, atopy patch test.
Bolded value: the number of children in the intervention group was not specified, we therefore approached the unknown as stated in the method section “Analysis”.