Table 5.
Overview of studies on the 4-food elimination diet.
| Level | Author, publication year | Mean age (years) | n | Period | Duration of diet | PPI | Diet (Exclusion of) | Histological response (eos/HPF) | Remission rate | |
|---|---|---|---|---|---|---|---|---|---|---|
| A | Kagalwalla, 2017 | 9,01 (1–18) |
78 | 2011-2016 | 6-8 weeks | Yes, NR | Cow’s milk, wheat, egg & soy | < 15 | 64% | |
| A | Molina-Infante, 2018 | 11 (5–13) |
9 | 2014-2016 | 6 weeks | Yes, NR | Dairy products, gluten-containing cereals, egg, legumes & peanuts | < 15 | 57% | |
| D | Gonsalves 2013 |
9 | 15 | NA | 6 weeks | NA | Cow’s milk, wheat, egg & soy | >50% reduction | 87% | |
| D | Kliewer, 2019 |
6-17 | 25 | NA | 12 weeks | NA | Cow’s milk, wheat, egg & soy | < 15 | 41% | |
NA, not applicable; PPI, proton pump inhibitors; NR, non-responder; R, responder; eos/HPF, eosinophils per high-power field.