Table 7.
Overview of studies on the cow’s milk elimination diet.
| Level | Author, publication year | Mean age (years) | n | Period | Duration of diet | PPI | Histological response(eos/HPF) | Remission rate |
|---|---|---|---|---|---|---|---|---|
| A | Kruszewski, 2016 | 2-18 | 14 | 2012-2014 | 6-8 weeks | Yes | < 15 | 64% |
| B | Kagalwalla, 2012 | 5,5 (1–12) | 17 | 2006-2011 | 6 weeks | R & NR | < 15 | 65% |
| B | Leung, 2015 | 13 (8–18) | 20 | 2007-2013 | 8 weeks | Yes, NR | < 10 | 65% |
| B | Teoh, 2019 | 9 (1–16) | 24 | 2013-2016 | Median 3 months |
NR | < 15 | 67% |
| C | Spergel, 2012 | 6,4 (1–18) | 35 | 2000-2011 | NA | NR | < 15 | 30% |
| C | Wong, 2020 | 9,9 (0,6-20,8) | 102 | NA | Mean 100,4 days |
NA | < 15 | 57% |
| D | Wechsler, 2017 | NA | 30 | NA | 6-8 weeks | NA | < 15 | 43% |
| D | Kliewer, 2019 |
6 to 17 | 38 | NA | 12 weeks | NA | < 15 | 44% |
NA, not applicable; PPI, proton pump inhibitors; NR, non-responder; R, responder; eos/HPF, eosinophils per high-power.
Bolded value: the number of children in the intervention group was not specified, we therefore approached the unknown as stated in the method section “Analysis”.