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. Author manuscript; available in PMC: 2021 Jun 2.
Published in final edited form as: Anticancer Res. 2017 Sep;37(9):4873–4879. doi: 10.21873/anticanres.11896

Table II.

Association of BIM mean IHC scores with clinicopathological characteristics.

N Mean IHC score (95%CI) p-Value

Diagnostic category <0.001
 Normal 254 0.24 (0.17–0.32)
 CIN I 59 0.64 (0.39–0.89)
 CIN II and III 216 3.32 (2.91–3.74)
 Cervical cancer 164 2.65 (2.25–3.05)
FIGO stage 0.041
 I 111 2.34 (1.88–2.80)
 II 47 3.15 (2.36–3.94)
 IV 6 4.50 (0.64–8.36)
Tumor differentiation 0.001
 Well + Moderate 96 3.06 (2.50–3.62)
 Poor 62 1.74 (1.24–2.24)
Cell Type 0.008
 Squamous cell carcinoma 137 2.89 (2.46–3.32)
 Others 27 1.44 (0.44–2.45)
Tumor size 0.742
 <4 cm 115 2.61 (2.12–3.10)
 ≥4 cm 49 2.76 (2.04–3.47)
Lymphovascular invasion 0.554
 Negative 81 2.56 (2.03–3.08)
 Positive 66 2.32 (1.71–2.93)
Lymph node (LN) metastasis 0.213
 Negative 111 2.31 (1.91–2.70)
 Positive 38 2.87 (1.84–3.89)
Radiation sensitivity 0.049
 Sensitive 36 3.06 (2.01–4.10)
 Resistant 16 1.75 (0.91–2.59)

CIN: Cervical intraepithelial neoplasia; FIGO: International Federation of Gynecology and Obstetrics; CI: confidence interval.