Table II.
N | Mean IHC score (95%CI) | p-Value | |
---|---|---|---|
Diagnostic category | <0.001 | ||
Normal | 254 | 0.24 (0.17–0.32) | |
CIN I | 59 | 0.64 (0.39–0.89) | |
CIN II and III | 216 | 3.32 (2.91–3.74) | |
Cervical cancer | 164 | 2.65 (2.25–3.05) | |
FIGO stage | 0.041 | ||
I | 111 | 2.34 (1.88–2.80) | |
II | 47 | 3.15 (2.36–3.94) | |
IV | 6 | 4.50 (0.64–8.36) | |
Tumor differentiation | 0.001 | ||
Well + Moderate | 96 | 3.06 (2.50–3.62) | |
Poor | 62 | 1.74 (1.24–2.24) | |
Cell Type | 0.008 | ||
Squamous cell carcinoma | 137 | 2.89 (2.46–3.32) | |
Others | 27 | 1.44 (0.44–2.45) | |
Tumor size | 0.742 | ||
<4 cm | 115 | 2.61 (2.12–3.10) | |
≥4 cm | 49 | 2.76 (2.04–3.47) | |
Lymphovascular invasion | 0.554 | ||
Negative | 81 | 2.56 (2.03–3.08) | |
Positive | 66 | 2.32 (1.71–2.93) | |
Lymph node (LN) metastasis | 0.213 | ||
Negative | 111 | 2.31 (1.91–2.70) | |
Positive | 38 | 2.87 (1.84–3.89) | |
Radiation sensitivity | 0.049 | ||
Sensitive | 36 | 3.06 (2.01–4.10) | |
Resistant | 16 | 1.75 (0.91–2.59) |
CIN: Cervical intraepithelial neoplasia; FIGO: International Federation of Gynecology and Obstetrics; CI: confidence interval.